NAD+ 5MG Peptide - 99% Pure Peptide | PeptiUAE

NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme found in all living cells. It is essential for fundamental metabolic processes and cellular maintenance.

Scientific Overview

In biochemical research, NAD+ functions as a primary electron acceptor and donor in redox reactions. Its roles include:

• Energy Metabolism: It is an indispensable cofactor for enzymes involved in glycolysis, the citric acid cycle (Krebs cycle), and oxidative phosphorylation, facilitating the conversion of nutrients into cellular energy (ATP).

• Enzymatic Regulation: NAD+ serves as a necessary substrate for several enzyme families, most notably:

  • Sirtuins (SIRTs): Involved in the regulation of cellular stress responses, aging processes, and gene expression.

  • PARPs (Poly ADP-ribose polymerases): Essential for DNA repair and genomic stability.

  • CD38: Involved in the regulation of intracellular calcium signaling.

• Redox Homeostasis: By cycling between its oxidized (NAD+) and reduced (NADH) forms, the molecule maintains the redox state of the cell, which is required for various biosynthetic pathways.

Technical Specifications

• Chemical Name: Nicotinamide Adenine Dinucleotide

• Molecular Formula: C₂₁H₂₇N₇O₁₄P₂

• Molecular Weight: Approximately 663.4 g/mol

• Appearance: Typically supplied as a white to off-white lyophilized powder.

• Solubility: Highly soluble in water and aqueous buffer systems.

• Analytical Verification: Identity and purity are typically confirmed via HPLC and UV-visible spectroscopy.

Storage and Handling

• Long-term Storage: Should be stored at -20°C or -80°C in a desiccated, moisture-free environment to prevent hydrolysis.

• Stability: The molecule is sensitive to moisture, heat, and alkaline conditions; solutions should be prepared fresh and kept on ice during experimental use.

• Reconstitution: Avoid repeated freeze-thaw cycles.

Research Use Disclaimer

For laboratory research purposes only. This material is not for human or veterinary use, nor for any cosmetic, food, or therapeutic applications. It is not approved by any regulatory agency for clinical use.