Epithalon 10MG Peptide - 99% Pure Peptide | PeptiUAE

Epithalon (also known as Epitalon or AEDG) is a synthetic tetrapeptide consisting of the amino acid sequence Ala-Glu-Asp-Gly. It was developed as a synthetic analogue of Epithalamin, a polypeptide complex originally extracted from the bovine pineal gland.

Scientific Overview

In laboratory and in vitro research, Epithalon is primarily studied for its potential biological effects on cellular and systemic aging markers. Key areas of ongoing preclinical investigation include:

• Telomerase Activity: Research has examined its ability to upregulate telomerase activity, which is associated with the maintenance of telomere length in various cell cultures.

• Neuroendocrine Function: Studies have explored its impact on the pineal gland and the synthesis of melatonin, as well as its interaction with neurotrophic and antioxidant pathways.

• Gene Expression: Investigations have looked into how the peptide may regulate gene expression in specific tissues, particularly concerning cell cycle regulation and anti-mutagenic pathways.

Technical Specifications

• Chemical Name: L-Alanyl-L-glutamyl-L-aspartyl-glycine

• Molecular Formula: C₁₄H₂₂N₄O₉

• Molecular Weight: Approximately 390.35 g/mol

• Form: Typically supplied as a lyophilized (freeze-dried) powder.

• Solubility: Soluble in water, PBS, and standard aqueous laboratory buffers.

• Analytical Verification: Identity and purity are typically confirmed via HPLC and mass spectrometry.

Storage and Handling

• Long-term Storage: Store at -20°C in a desiccated, moisture-free environment.

• Reconstitution: Usually reconstituted in sterile water or appropriate laboratory buffers for experimental use.

• Stability: To maintain structural integrity, avoid repeated freeze-thaw cycles once the material is in solution.

Research Use Disclaimer

For laboratory research purposes only. This material is not for human or veterinary use, nor for any cosmetic, food, or therapeutic applications. It is not approved by any regulatory agency for clinical use, and its safety profile for human administration has not been established through rigorous, large-scale clinical trials.