PT-141 5MG Peptide - 99% Pure Peptide | PeptiUAE

PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide. It is a modification of the melanotan II peptide, specifically designed by removing the C-terminal amide group.

Scientific Overview

In laboratory and in vitro research, PT-141 is studied for its role as a non-selective agonist of the melanocortin receptors (MCRs), particularly the MC3R and MC4R subtypes within the central nervous system.

• Mechanism of Action: Unlike other melanocortin analogues that primarily induce skin pigmentation, PT-141 is investigated for its activation of central pathways associated with physiological arousal and signaling.

• Molecular Composition: It has a molecular formula of $C_{50}H_{68}N_{14}O_{10}$ and a molecular weight of approximately 1025.2 g/mol.

• Experimental Use: Research focuses on its biochemical interactions with the melanocortin system to study signal transduction, neuronal firing patterns, and behavioral responses in controlled, non-human experimental models.

Technical Specifications

• Chemical Name: Bremelanotide (PT-141)

• Appearance: Typically supplied as a lyophilized (freeze-dried) powder.

• Solubility: Soluble in sterile water, PBS, or standard aqueous laboratory buffer systems.

• Storage: Maintain at -20°C in a desiccated, moisture-free environment for long-term stability. Avoid repeated freeze-thaw cycles once the material is reconstituted to maintain structural integrity.

• Analytical Verification: Identity and purity are typically confirmed via HPLC and mass spectrometry.

Research Use Disclaimer

For laboratory research purposes only. This material is not for human or veterinary use, nor for any cosmetic, food, or therapeutic applications. It is not approved by any regulatory agency for clinical use.