{"product_id":"kisspeptin-5mg-peptide","title":"Kisspeptin 5MG Peptide - 99% Pure Peptide | PeptiUAE","description":"\u003cp data-path-to-node=\"0\"\u003eKisspeptin refers to a family of bioactive peptides encoded by the \u003ci data-path-to-node=\"0\" data-index-in-node=\"67\"\u003eKISS1\u003c\/i\u003e gene. Originally identified in 1996 for its potential to suppress metastasis in melanoma cells (initially named \"metastin\"), it is now primarily recognized for its central role in regulating the mammalian reproductive axis.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"1\"\u003eScientific Overview\u003c\/h3\u003e\n\u003cp data-path-to-node=\"2\"\u003eIn laboratory research, kisspeptin is studied for its function as an upstream mediator of the hypothalamic-pituitary-gonadal (HPG) axis:\u003c\/p\u003e\n\u003cul data-path-to-node=\"3\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,0,0\"\u003e\u003cb data-path-to-node=\"3,0,0\" data-index-in-node=\"0\"\u003eMechanisms of Action:\u003c\/b\u003e Kisspeptin binds to its specific receptor, the kisspeptin receptor (\u003cb data-path-to-node=\"3,0,0\" data-index-in-node=\"90\"\u003eKISS1R\u003c\/b\u003e, also known as GPR54). This interaction stimulates the secretion of gonadotropin-releasing hormone (GnRH) from the hypothalamus, which subsequently triggers the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,1,0\"\u003e\u003cb data-path-to-node=\"3,1,0\" data-index-in-node=\"0\"\u003eMolecular Forms:\u003c\/b\u003e The human \u003ci data-path-to-node=\"3,1,0\" data-index-in-node=\"27\"\u003eKISS1\u003c\/i\u003e gene encodes a precursor protein that is proteolytically cleaved into several bioactive fragments, including \u003cb data-path-to-node=\"3,1,0\" data-index-in-node=\"142\"\u003ekisspeptin-54 (KP-54)\u003c\/b\u003e, \u003cb data-path-to-node=\"3,1,0\" data-index-in-node=\"165\"\u003ekisspeptin-14\u003c\/b\u003e, \u003cb data-path-to-node=\"3,1,0\" data-index-in-node=\"180\"\u003ekisspeptin-13\u003c\/b\u003e, and \u003cb data-path-to-node=\"3,1,0\" data-index-in-node=\"199\"\u003ekisspeptin-10\u003c\/b\u003e. These variants act as agonists of KISS1R with similar affinity and efficacy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"3,2,0\"\u003e\u003cb data-path-to-node=\"3,2,0\" data-index-in-node=\"0\"\u003eResearch Applications:\u003c\/b\u003e Current preclinical and clinical research explores the kisspeptin system as a therapeutic target for various reproductive hormonal disorders and metabolic conditions.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"4\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul data-path-to-node=\"5\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"5,0,0\"\u003e\u003cb data-path-to-node=\"5,0,0\" data-index-in-node=\"0\"\u003eGene\/Protein Source:\u003c\/b\u003e Encoded by the \u003ci data-path-to-node=\"5,0,0\" data-index-in-node=\"36\"\u003eKISS1\u003c\/i\u003e gene (humans).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"5,1,0\"\u003e\u003cb data-path-to-node=\"5,1,0\" data-index-in-node=\"0\"\u003eReceptor:\u003c\/b\u003e KISS1R (G-protein coupled receptor).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"5,2,0\"\u003e\u003cb data-path-to-node=\"5,2,0\" data-index-in-node=\"0\"\u003eBiological Role:\u003c\/b\u003e Regulator of GnRH secretion and the HPG axis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"5,3,0\"\u003e\u003cb data-path-to-node=\"5,3,0\" data-index-in-node=\"0\"\u003eStorage:\u003c\/b\u003e For laboratory-grade peptides, long-term storage is typically maintained at \u003cb data-path-to-node=\"5,3,0\" data-index-in-node=\"85\"\u003e-20°C\u003c\/b\u003e or lower in a desiccated, moisture-free environment. Avoid repeated freeze-thaw cycles once the material is reconstituted to maintain structural integrity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"6\"\u003eResearch Use Disclaimer\u003c\/h3\u003e\n\u003cp data-path-to-node=\"7\"\u003e\u003cb data-path-to-node=\"7\" data-index-in-node=\"0\"\u003eFor laboratory research purposes only.\u003c\/b\u003e This material is not for human or veterinary use, nor for any cosmetic, food, or therapeutic applications. It is not approved by any regulatory agency for clinical use.\u003c\/p\u003e","brand":"PeptiUAE","offers":[{"title":"Single Vial","offer_id":48801181958388,"sku":null,"price":349.0,"currency_code":"AED","in_stock":true},{"title":"2 Vials","offer_id":48801181991156,"sku":null,"price":549.0,"currency_code":"AED","in_stock":true},{"title":"4 Vials","offer_id":48801182023924,"sku":null,"price":849.0,"currency_code":"AED","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0837\/7889\/6116\/files\/Kisspeptin.jpg?v=1783009291","url":"https:\/\/peptiuae.com\/products\/kisspeptin-5mg-peptide","provider":"My Store","version":"1.0","type":"link"}